Synonyms
Alcohol amnesic disorder; Alcoholic polyneuropathy; Alcoholic psychosis; Korsakoff (korsakov) psychosis; Wernicke’s encephalitis; Wernicke-Korsakoff encephalopathy
Short Description or Definition
Korsakoff’s psychosis (KP) is an abnormal mental condition that is usually a sequela of chronic alcoholism. Generally considered a later stage of Wernicke’s encephalopathy (WE), KP is associated with polyneuritis and is characterized by an impaired ability to acquire new information and by a substantial, but irregular, memory loss for which the patient often attempts to compensate through confabulation. However, KP is often distinguished from dementia associated with alcoholism due to the preservation of major intellectual ability, which is clouded in the latter syndrome.
Categorization
Korsakoff’s psychosis is usually associated with the late, irreversible stage of Wernicke’s encephalitis. WE is an acute neuropsychiatric condition resulting from an initially reversible dysfunction...
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References and Readings
Laas, R., & Hagel, C. (2000). Neuropathology of chronic alcoholism. Clinical Neuropathology, 19(5), 252–253.
Logan, C., Asadi, H., Kok, H. K., Looby, S. T., Brennan, P., O’Hare, A., & Thorton, J. (2016). Neuroimaging of chronic alcohol misuse. Journal of Medical Imaging and Radiation Oncology. https://doi.org/10.1111/1754-9485.12572. [Epub ahead of print].
Manzardo, A. M., & Penick, E. C. (2006). A theoretical argument for inherited thiamine insensitivity as one possible biological cause of familial alcoholism. Alcoholism: Clinical and Experimental Research, 30(9), 1545–1550.
McIntosh, C., & Chick, J. (2004). Alcohol and the nervous system. Journal of Neurology, Neurosurgery & Psychiatry, 75(Suppl 3), iii16–iii21.
McIntosh, C., & Chick, J. (2006). Managing neurological problems in heavy drinkers. Practitioner, 250(1685), 22, 25, 27–29 passim
Raichle, M. E., & Gusnard, D. A. (2002). Appraising the brain’s energy budget. Proceedings of the National Academy of Sciences USA, 99(16), 10237–10239.
Sechi, G., & Serra, A. (2007). Wernicke’s encephalopathy: New clinical settings and recent advances in diagnosis and management. Lancet Neurology, 6(5), 442–455.
Sharp, C. S., Wilson, M. P., & Nordstrom, K. (2016). Psychiatric emergencies for clinicians: Emergency Department Management of Wernicke-Korsakoff Syndrome. Journal of Emergency Medicine, 51(4), 401–404.
Sutherland, G. T., Sheedy, D., & Kril, J. J. (2014). Neuropathology of alcoholism. Handbook of Clinical Neurology, 125, 603–615.
Thomson, A. D. (2000). Mechanisms of vitamin deficiency in chronic alcohol misusers and the development of the Wernicke-Korsakoff syndrome. Alcohol and Alcoholism. Supplement, 35(1), 2–7.
Thomson, A. D., & Marshall, E. J. (2006a). The natural history and pathophysiology of Wernicke’s encephalopathy and Korsakoff’s psychosis. Alcohol and Alcoholism, 41(2), 151–158.
Thomson, A. D., & Marshall, E. J. (2006b). The treatment of patients at risk of developing Wernicke’s encephalopathy in the community. Alcohol and Alcoholism, 41(2), 159–167.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG, part of Springer Nature
About this entry
Cite this entry
Churn, S.B., Campbell, J. (2018). Korsakoff’s Syndrome. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_327
Download citation
DOI: https://doi.org/10.1007/978-3-319-57111-9_327
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-57110-2
Online ISBN: 978-3-319-57111-9
eBook Packages: Behavioral Science and PsychologyReference Module Humanities and Social SciencesReference Module Business, Economics and Social Sciences