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Arteriovenous Malformation (AVM)

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Synonyms

Brain arteriovenous malformation; Cerebral malformation; Vascular malformation

Short Description or Definition

Arteriovenous malformations (AVMs) are irregular, anomalous, abnormal, or faulty formations or structures connecting the arteries and veins (Webster 2006). Intracranial hemorrhage is a potential complication in patients with arteriovenous malformations of the brain (AMB) (Stapf et al. 2006).

Etiology

AVMs arise about 3 weeks after conception, at the time when blood vessels are dividing into veins and arteries (Stein and Wolpertson 1980). It has been suggested that AVMs are dynamic and have the ability to grow, regress, and regenerate following obliteration by surgery or radiosurgery (Moftakhar et al. 2009). It is hypothesized that the altered expression of more than 900 genes is involved in the pathogenesis of AVMs (Moftakhar et al. 2009).

Epidemiology

AVMs are the most common type of clinically significant vascular malformation, occurring almost exclusively in the...

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References and Readings

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Correspondence to Bruce J. Diamond .

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Diamond, B.J., Mosley, J.E. (2018). Arteriovenous Malformation (AVM). In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_2158

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