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Carbohydrate-Based Nanofibers: Applications and Potentials

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Handbook of Nanofibers

Abstract

Carbohydrate polymers have recently attracted great interest from academia and industry as one of the most abundant polymers in the world. Homopolymers or copolymers of monosaccharides, known as polysaccharides, are important part of carbohydrates and polymer materials with different sources from plants, microbes, and animals. Various structures and sources provide different chemical and mechanical properties and in result different applications. Carbohydrates are inexpensive materials, easily available, and renewable resources which present important characteristics including hydrophilicity and biocompatibility into polymeric systems. In this chapter potentials and applications of carbohydrate materials such as chitosan, chitin, cellulose, and alginate or their combinations in nanofiber form will be reviewed.

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References

  1. Zhao W et al (2015) Preparation of animal polysaccharides nanofibers by electrospinning and their potential biomedical applications. J Biomed Mater Res A 103(2):807–818

    Article  Google Scholar 

  2. Bhattarai N, Zhang M (2007) Controlled synthesis and structural stability of alginate-based nanofibers. Nanotechnology 18(45):455601

    Article  Google Scholar 

  3. Lee KY et al (2009) Electrospinning of polysaccharides for regenerative medicine. Adv Drug Deliv Rev 61(12):1020–1032

    Article  CAS  Google Scholar 

  4. Nie H et al (2008) Effects of chain conformation and entanglement on the electrospinning of pure alginate. Biomacromolecules 9(5):1362–1365

    Article  CAS  Google Scholar 

  5. Lee YJ et al (2007) Preparation of atactic poly (vinyl alcohol)/sodium alginate blend nanowebs by electrospinning. J Appl Polym Sci 106(2):1337–1342

    Article  CAS  Google Scholar 

  6. De Vrieze S et al (2007) Electrospinning of chitosan nanofibrous structures: feasibility study. J Mater Sci 42(19):8029–8034

    Article  CAS  Google Scholar 

  7. Ojha SS et al (2008) Fabrication and characterization of electrospun chitosan nanofibers formed via templating with polyethylene oxide. Biomacromolecules 9(9):2523–2529

    Article  CAS  Google Scholar 

  8. Chen J-P, Chang G-Y, Chen J-K (2008) Electrospun collagen/chitosan nanofibrous membrane as wound dressing. Colloids Surf A Physicochem Eng Asp 313:183–188

    Article  Google Scholar 

  9. Liu H, Hsieh YL (2003) Surface methacrylation and graft copolymerization of ultrafine cellulose fibers. J Polym Sci B Polym Phys 41(9):953–964

    Article  CAS  Google Scholar 

  10. Wu X et al (2005) Effect of solvent on morphology of electrospinning ethyl cellulose fibers. J Appl Polym Sci 97(3):1292–1297

    Article  CAS  Google Scholar 

  11. Frenot A, Henriksson MW, Walkenström P (2007) Electrospinning of cellulose-based nanofibers. J Appl Polym Sci 103(3):1473–1482

    Article  CAS  Google Scholar 

  12. Nasri-Nasrabadi B et al (2014) Porous starch/cellulose nanofibers composite prepared by salt leaching technique for tissue engineering. Carbohydr Polym 108:232–238

    Article  CAS  Google Scholar 

  13. Toskas G et al (2013) Chitosan (PEO)/silica hybrid nanofibers as a potential biomaterial for bone regeneration. Carbohydr Polym 94(2):713–722

    Article  CAS  Google Scholar 

  14. Tang J et al (2017) Preparation of paclitaxel/chitosan co-assembled core-shell nanofibers for drug-eluting stent. Appl Surf Sci 393:299–308

    Article  CAS  Google Scholar 

  15. Luo Y et al (2013) Carbon nanotube-incorporated multilayered cellulose acetate nanofibers for tissue engineering applications. Carbohydr Polym 91(1):419–427

    Article  CAS  Google Scholar 

  16. Nie H et al (2011) Electrospinning and characterization of konjac glucomannan/chitosan nanofibrous scaffolds favoring the growth of bone mesenchymal stem cells. Carbohydr Polym 85(3):681–686

    Article  CAS  Google Scholar 

  17. Du J et al (2014) Comparative evaluation of chitosan, cellulose acetate, and polyethersulfone nanofiber scaffolds for neural differentiation. Carbohydr Polym 99:483–490

    Article  CAS  Google Scholar 

  18. Deng H et al (2010) Layer-by-layer structured polysaccharides film-coated cellulose nanofibrous mats for cell culture. Carbohydr Polym 80(2):474–479

    Article  CAS  Google Scholar 

  19. Majd SA et al (2016) Application of Chitosan/PVA Nano fiber as a potential wound dressing for streptozotocin-induced diabetic rats. Int J Biol Macromol 92:1162–1168

    Article  Google Scholar 

  20. Entekhabi E et al (2016) Design and manufacture of neural tissue engineering scaffolds using hyaluronic acid and polycaprolactone nanofibers with controlled porosity. Mater Sci Eng C 69:380–387

    Article  CAS  Google Scholar 

  21. Jeong SI et al (2010) Electrospun alginate nanofibers with controlled cell adhesion for tissue engineering. Macromol Biosci 10(8):934–943

    Article  CAS  Google Scholar 

  22. Jeong SI et al (2012) Biodegradable photo-crosslinked alginate nanofibre scaffolds with tuneable physical properties, cell adhesivity and growth factor release. Eur Cell Mater 24:331

    Article  CAS  Google Scholar 

  23. Kaya M et al (2016) Porous and nanofiber α-chitosan obtained from blue crab (Callinectes sapidus) tested for antimicrobial and antioxidant activities. LWT-Food Sci Technol 65:1109–1117

    Article  CAS  Google Scholar 

  24. Abdelgawad AM et al (2017) Fabrication and characterization of bactericidal thiol-chitosan and chitosan iodoacetamide nanofibres. Int J Biol Macromol 94:96–105

    Article  CAS  Google Scholar 

  25. Bienek DR, Hoffman KM, Tutak W (2016) Blow-spun chitosan/PEG/PLGA nanofibers as a novel tissue engineering scaffold with antibacterial properties. J Mater Sci Mater Med 27(9):146

    Article  Google Scholar 

  26. Lee SJ et al (2014) Electrospun chitosan nanofibers with controlled levels of silver nanoparticles. Preparation, characterization and antibacterial activity. Carbohydr Polym 111:530–537

    Article  CAS  Google Scholar 

  27. Song J et al (2016) Antibacterial effects of electrospun chitosan/poly (ethylene oxide) nanofibrous membranes loaded with chlorhexidine and silver. Nanomedicine 12(5):1357–1364

    Article  CAS  Google Scholar 

  28. Cai N et al (2016) Tailoring mechanical and antibacterial properties of chitosan/gelatin nanofiber membranes with Fe 3 O 4 nanoparticles for potential wound dressing application. Appl Surf Sci 369:492–500

    Article  CAS  Google Scholar 

  29. Kaassis AY et al (2014) Pulsatile drug release from electrospun poly (ethylene oxide)–sodium alginate blend nanofibres. J Mater Chem B 2(10):1400–1407

    Article  CAS  Google Scholar 

  30. Shi X et al (2014) pH-and electro-response characteristics of bacterial cellulose nanofiber/sodium alginate hybrid hydrogels for dual controlled drug delivery. RSC Adv 4(87):47056–47065

    Article  CAS  Google Scholar 

  31. Yu D-G et al (2012) Modified coaxial electrospinning for the preparation of high-quality ketoprofen-loaded cellulose acetate nanofibers. Carbohydr Polym 90(2):1016–1023

    Article  CAS  Google Scholar 

  32. Ma H et al (2011) Ultrafine polysaccharide nanofibrous membranes for water purification. Biomacromolecules 12(4):970–976

    Article  CAS  Google Scholar 

  33. Ma H, Hsiao BS, Chu B (2011) Ultrafine cellulose nanofibers as efficient adsorbents for removal of UO22+ in water. ACS Macro Lett 1(1):213–216

    Article  Google Scholar 

  34. Li Y et al (2016) Crosslinked chitosan nanofiber mats fabricated by one-step electrospinning and ion-imprinting methods for metal ions adsorption. Sci China Chem 59(1):95–105

    Article  CAS  Google Scholar 

  35. Li L, Li Y, Yang C (2016) Chemical filtration of Cr (VI) with electrospun chitosan nanofiber membranes. Carbohydr Polym 140:299–307

    Article  CAS  Google Scholar 

  36. Li Z et al (2016) Preparation of chitosan/polycaprolactam nanofibrous filter paper and its greatly enhanced chromium (VI) adsorption. Colloids Surf A Physicochem Eng Asp 494:65–73

    Article  CAS  Google Scholar 

  37. Wang L et al (2016) Needleless electrospinning for scaled-up production of ultrafine chitosan hybrid nanofibers used for air filtration. RSC Adv 6(107):105988–105995

    Article  CAS  Google Scholar 

  38. Min L-L et al (2016) Functionalized chitosan electrospun nanofiber for effective removal of trace arsenate from water. Sci Rep 6:32480

    Article  Google Scholar 

  39. Cui G et al (2016) Synthesis of a ferric hydroxide-coated cellulose nanofiber hybrid for effective removal of phosphate from wastewater. Carbohydr Polym 154:40–47

    Article  CAS  Google Scholar 

  40. Chitpong N, Husson SM (2017) Polyacid functionalized cellulose nanofiber membranes for removal of heavy metals from impaired waters. J Membr Sci 523:418–429

    Article  CAS  Google Scholar 

  41. Gomathi P et al (2011) Fabrication of novel chitosan nanofiber/gold nanoparticles composite towards improved performance for a cholesterol sensor. Sensors Actuators B Chem 153(1):44–49

    Article  CAS  Google Scholar 

  42. El-Moghazy A et al (2016) Biosensor based on electrospun blended chitosan-poly (vinyl alcohol) nanofibrous enzymatically sensitized membranes for pirimiphos-methyl detection in olive oil. Talanta 155:258–264

    Article  CAS  Google Scholar 

  43. Pourjavaher S et al (2017) Development of a colorimetric pH indicator based on bacterial cellulose nanofibers and red cabbage (Brassica oleracea) extract. Carbohydr Polym 156:193–201

    Article  CAS  Google Scholar 

  44. Liou P et al (2017) Cellulose nanofibers coated with silver nanoparticles as a SERS platform for detection of pesticides in apples. Carbohydr Polym 157:643–650

    Article  CAS  Google Scholar 

  45. Srbová J et al (2016) Covalent biofunctionalization of chitosan nanofibers with trypsin for high enzyme stability. React Funct Polym 104:38–44

    Article  Google Scholar 

  46. Park J-M et al (2013) Immobilization of lysozyme-CLEA onto electrospun chitosan nanofiber for effective antibacterial applications. Int J Biol Macromol 54:37–43

    Article  CAS  Google Scholar 

  47. Doğaç Yİ et al (2017) A comparative study for lipase immobilization onto alginate based composite electrospun nanofibers with effective and enhanced stability. Int J Biol Macromol 96:302–311

    Article  Google Scholar 

  48. Huang X-J, Ge D, Xu Z-K (2007) Preparation and characterization of stable chitosan nanofibrous membrane for lipase immobilization. Eur Polym J 43(9):3710–3718

    Article  CAS  Google Scholar 

  49. Xu W et al (2017) Preparation and characterization of electrospun alginate/PLA nanofibers as tissue engineering material by emulsion electrospinning. J Mech Behav Biomed Mater 65:428–438

    Article  CAS  Google Scholar 

  50. Chae T et al (2013) Novel biomimetic hydroxyapatite/alginate nanocomposite fibrous scaffolds for bone tissue regeneration. J Mater Sci Mater Med 24(8):1885–1894

    Article  CAS  Google Scholar 

  51. Sarhan WA, Azzazy HM, El-Sherbiny IM (2016) Honey/chitosan nanofiber wound dressing enriched with Allium Sativum and cleome droserifolia: enhanced antimicrobial and wound healing activity. ACS Appl Mater Interfaces 8(10):6379–6390

    Article  CAS  Google Scholar 

  52. Pillay V et al (2013) A review of the effect of processing variables on the fabrication of electrospun nanofibers for drug delivery applications. J Nanomater 2013:789289

    Article  Google Scholar 

  53. Karimi M et al (2016) Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems. Chem Soc Rev 45(5):1457–1501

    Article  CAS  Google Scholar 

  54. Reddy SM (2017) Membrane technologies for sensing and biosensing. In: Materials for chemical sensing, . pp 75–103. Springer, Hindawi

    Google Scholar 

  55. Sulaiman S et al (2015) A review: potential usage of cellulose nanofibers (CNF) for enzyme immobilization via covalent interactions. Appl Biochem Biotechnol 175(4):1817–1842

    Article  CAS  Google Scholar 

  56. Brinchi L et al (2013) Production of nanocrystalline cellulose from lignocellulosic biomass: technology and applications. Carbohydr Polym 94(1):154–169

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Medical Nanotechnology, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran

    Sajad Bahrami, Bita Mehravi & Masoumeh Zahmatkeshan

  2. Student Research Committee, Iran University of Medical Sciences, Tehran, Iran

    Sajad Bahrami

  3. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran

    Moein Adel, Fariba Esmaeili & Seyed Mahdi Rezayat

  4. Deputy of Research and Technology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran

    Moein Adel

  5. Department of Medical Nanotechnology, School of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran

    Moein Adel

  6. Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

    Seyed Mahdi Rezayat

  7. Neuroscience Research Center (NRC), Iran University of Medical Sciences, Tehran, Iran

    Masoumeh Zahmatkeshan

  8. Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran

    Bita Mehravi & Masoumeh Zahmatkeshan

Authors
  1. Sajad Bahrami
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  2. Moein Adel
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  3. Fariba Esmaeili
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  4. Seyed Mahdi Rezayat
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  5. Bita Mehravi
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  6. Masoumeh Zahmatkeshan
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Corresponding author

Correspondence to Masoumeh Zahmatkeshan .

Editor information

Editors and Affiliations

  1. Institut Européen des Membranes (IEMM, ENSCM UM CNRS UMR5635), Montpellier, France

    Ahmed Barhoum

  2. Institut Européen des Membranes, IEM – UMR 5635, ENSCM, CNRS Univ Montpellier, Montpellier, France

    Mikhael Bechelany

  3. University of Texas Rio Grande Valley, Edinburg, TX, USA

    Abdel Salam Hamdy Makhlouf

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Bahrami, S., Adel, M., Esmaeili, F., Rezayat, S.M., Mehravi, B., Zahmatkeshan, M. (2019). Carbohydrate-Based Nanofibers: Applications and Potentials. In: Barhoum, A., Bechelany, M., Makhlouf, A. (eds) Handbook of Nanofibers. Springer, Cham. https://doi.org/10.1007/978-3-319-53655-2_28

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