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Application of Nanofibers in Ophthalmic Tissue Engineering

Handbook of Nanofibers

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Abstract

This chapter describes recently designed and developed nanofiber scaffolds used for ophthalmic tissue engineering applications. In recent decades, ophthalmic diseases have been a significant health concern throughout the world, and the prevalence is likely to increase, especially in developing countries. Many types of research have focused on ophthalmic disease remedies, as well as corneal transplantation, retinal detachment, and preparation of an appropriate system for regeneration of the cornea and retina by use of scaffolds. Therefore, a necessary property for scaffold materials—in addition to biocompatibility, mechanical strength, and permeability to glucose and other nutrients—is the ability to encourage cell adhesion, which could allow artificial scaffolds to be fixed in place. However, the topography of materials has an significant effect on their applications, particularly in ophthalmic tissue engineering. Recently, nanofibers have attracted attention because of their unique properties for preparation of biodegradable and nonbiodegradable scaffolds. Electrospinning is a method used to produce biocompatible scaffolds from nanofibers for the purpose of tissue regeneration. Nanofibers can produce three-dimensional scaffolds for various purposes in ophthalmic applications such as corneal transplantation and retinal regeneration.

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Authors and Affiliations

  1. Nano Fusion Technology Research Group, Division of Frontier Fibers, Institute for Fiber Engineering (IFES), Interdisciplinary Cluster for Cutting Edge Research (ICCER), Shinshu University, Ueda, Nagano, Japan

    Davood Kharaghani, Muhammad Qamar Khan & Ick Soo Kim

Authors
  1. Davood Kharaghani
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  2. Muhammad Qamar Khan
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  3. Ick Soo Kim
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Correspondence to Ick Soo Kim .

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Editors and Affiliations

  1. Vrije Universiteit Brussel (VUB), Department of Materials and Chemistry (M Vrije Universiteit Brussel (VUB), Brussels, Belgium

    Ahmed Barhoum

  2. Montpellier, France

    Mikhael Bechelany

  3. University of Texas Rio Grande Valley , Edinburg, USA

    Abdel Makhlouf

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Kharaghani, D., Qamar Khan, M., Soo Kim, I. (2019). Application of Nanofibers in Ophthalmic Tissue Engineering. In: Barhoum, A., Bechelany, M., Makhlouf, A. (eds) Handbook of Nanofibers. Springer, Cham. https://doi.org/10.1007/978-3-319-42789-8_56-1

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  • DOI: https://doi.org/10.1007/978-3-319-42789-8_56-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-42789-8

  • Online ISBN: 978-3-319-42789-8

  • eBook Packages: Springer Reference Chemistry and Mat. ScienceReference Module Physical and Materials ScienceReference Module Chemistry, Materials and Physics

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  1. Latest

    Application of Nanofibers in Ophthalmic Tissue Engineering
    Published:
    09 February 2019

    DOI: https://doi.org/10.1007/978-3-319-42789-8_56-2

  2. Original

    Application of Nanofibers in Ophthalmic Tissue Engineering
    Published:
    27 October 2018

    DOI: https://doi.org/10.1007/978-3-319-42789-8_56-1

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