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Molecular Basics on Genitourinary Malignancies

  • Living reference work entry
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Urologic Oncology

Abstract

We constantly face diagnostic and therapeutic challenges in the management of genitourinary malignancies. The lack of highly sensitive and specific cancer markers often results in the need of invasive procedures for both diagnostic and surveillance purposes. Understanding the molecular basics of genitourinary malignancies is essential for personalized and precision medicine. Cancers originating from the same organ could have different biological behaviours and responses towards different types of treatment. An individualized treatment based on molecular features could potentially enhance clinical effectiveness while minimizing treatment-related side effects. In this book chapter, we shall summarize the current knowledge regarding the molecular basics of genitourinary malignancies including prostate cancer, urothelial carcinoma of the bladder and upper urinary tract, kidney cancer, penile cancer and testicular cancer. We hope, by the end of the book chapter, we would be able to provide you insights regarding the next step forward.

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Authors and Affiliations

  1. Department of Chemical Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, Hong Kong

    Timothy Hua-Tse Cheng

  2. Division of Urology, Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong, Hong Kong

    Wayne Lam

  3. S.H. Ho Urology Centre, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, Hong Kong

    Jeremy Yuen-Chun Teoh

Authors
  1. Timothy Hua-Tse Cheng
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  2. Wayne Lam
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  3. Jeremy Yuen-Chun Teoh
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Corresponding author

Correspondence to Jeremy Yuen-Chun Teoh .

Editor information

Editors and Affiliations

  1. Dept. of Urology & Urologic Oncology, Hannover Medical School, Hannover, Germany

    Axel S. Merseburger

  2. Dept. of Urology, University of Regensburg St. Josef Medical Centre, Regensburg, Germany

    Maximilian Burger

Section Editor information

  1. Klinik und Poliklinik für Urologie, Universität Regensburg/Caritas-Krankenhaus St. Josef, Regensburg, Germany

    Maximilian Burger

  2. Department of Urology, University Hospital of Schleswig-Holstein, Luebeck, Germany

    Axel Stuart Merseburger

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Cheng, T.HT., Lam, W., Teoh, J.YC. (2018). Molecular Basics on Genitourinary Malignancies. In: Merseburger, A., Burger, M. (eds) Urologic Oncology. Springer, Cham. https://doi.org/10.1007/978-3-319-42603-7_45-1

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  • DOI: https://doi.org/10.1007/978-3-319-42603-7_45-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-42603-7

  • Online ISBN: 978-3-319-42603-7

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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