Synonyms
Benign papillomata; Malpighian papilloma
Definition
The upper gastrointestinal tract squamous papilloma described in this section will address exclusively the esophageal squamous papilloma. Anatomically, one could argue if pharyngeal squamous papilloma could also be included in this section, but it will be discussed in the squamous papilloma of the upper respiratory tractsection.
Esophageal squamous papilloma is a benign polypoid lesion that usually presents with a wart-like configuration at upper endoscopy. In general, the microscopic appearance of esophageal squamous papilloma is composed of a stromal core of lamina propria lined by mature stratified squamous epithelium.
Clinical Features
Incidence
Esophageal squamous papilloma is an uncommon lesion with less than 200 cases described in the worldwide literature.
The estimated incidence varies between 0.01% and 0.45%, in endoscopic series, while studies based on autopsies series reveal a prevalence of 0.006–0.04% of the...
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References and Further Reading
Attila, T., et al. (2009). Esophageal papillomatosis complicated by squamous cell carcinoma. Canadian Journal of Gastroenterology, 23, 415–419.
Bohn, O. L., et al. (2008). Identification of human papillomavirus in esophageal squamous papillomas. World Journal of Gastroenterology, 14, 7107–7111.
Brandt, L. J. (2011). Esophageal squamous papilloma. Gastrointestinal Endoscopy, 73, 1035.
Gomez, N. A., et al. (1997). Esophageal squamous papilloma: A case report and a review of the literature. Acta Gastroenterologica Latinoamericana, 27, 131–133.
Kanth, P., & Go, F. (2011). Squamous papilloma: An unusual esophageal entity. Endoscopy, 53, E405–E406.
Lewin, K. J., & Appelman, H. D. (1995). Tumors of theesophagus & stomach: Atlas of tumor pathology. In American registry of pathology (pp. 31–32). Washington, DC: Armed Forced Institute of Pathology.
Mosca, S., et al. (2001). Squamous papilloma of the esophagus: Long-term follow up. Journal of Gastroenterology and Hepatology, 16, 857–861.
Odze, R., & Goldblum, J. (2009). Surgical pathology of the GU tract, liver, billiary tract and pancreas (pp. 406–407). Philadelphia: Saunders Elsevier.
Odze, R., et al. (1993). Esophageal squamous papillomas: A clinicopathological study of 38 lesions and analysis for human papillomavirus by the polymerase chain reaction. American Journal of Surgical Pathology, 17, 803–812.
Rebeuh, J., et al. (2011). Esophageal squamous papilloma in children. Endoscopy, 43, E256.
Tabatabaei, S. A., et al. (2009). Giant esophageal squamous papilloma: A case report. Journal of Digestive Diseases, 10, 228–230.
Takeshita, K., et al. (2006). Clinicopathological characteristics of esophageal squamous papillomas in japonese patients – With comparison of findings from western countries. Acta Hitochemistry Cytochemistry, 39, 23–30.
Waterfall, W. E., et al. (1978). Benign oesophagealpapillomatosis. A case report with a review of the literature. Journal of Clinical Pathology, 31, 111–115.
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Marques, R.C., Chaves, P. (2017). Squamous Papilloma, Upper Gastrointestinal Tract. In: Carneiro, F., Chaves, P., Ensari, A. (eds) Pathology of the Gastrointestinal Tract. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-40560-5_1684
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DOI: https://doi.org/10.1007/978-3-319-40560-5_1684
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