Synonyms
Colloid carcinoma; Mucinous adenocarcinoma; Mucoid carcinoma
Definition
Mucinous carcinoma is one of the five main types of gastric adenocarcinoma in the World Health Organization (WHO) classification scheme. These adenocarcinomas are characterized by the production of abundant intracellular and extracellular mucus; by convention, more than 50% of the tumor consists of extracellular mucus.
Clinical Features
Incidence
Gastric carcinoma accounts for the fifth most common form of cancer worldwide. Mucinous gastric carcinoma compromises approximately 2–5% of all gastric carcinomas.
Age
Incidence increases progressively with age and is not different from other types of gastric carcinoma.
Sex
Men are more at risk of developing gastric cancer than women. In the study of Choi et al., 77% of patients with mucinous gastric carcinoma were men, while in non-mucinous gastric carcinoma, 67% were men.
Site
The entire stomach can be involved; most frequently, mucinous gastric carcinomas are...
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References and Further Reading
Bosman, F. T., Carneiro, F., Hruban, R. H., & Theise, N. D. (2010). WHO classification of tumours of the digestive system (4th ed.). Lyon: IARC.
Choi, J. S., Kim, M. A., Lee, H. E., Lee, H. S., & Kim, W. H. (2009). Mucinous gastric carcinomas: Clinicopathologic and molecular analyses. Cancer, 115(15), 3581–3590.
Chu, P. G., Chung, L., Weiss, L. M., & Lau, S. K. (2011). Determining the site of origin of mucinous adenocarcinoma: An immunohistochemical study of 175 cases. The American Journal of Surgical Pathology, 35(12), 1830–1836.
Sung, C. O., Lee, S. M., Choi, J. S., Kim, K. M., Choi, M. G., Noh, J. H., et al. (2012). Tumor size predicts survival in mucinous gastric carcinoma. Journal of Surgical Oncology, 106(6), 757–764.
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van der Post, C.R., Carneiro, F. (2017). Mucinous Carcinoma, Upper Gastrointestinal Tract. In: Carneiro, F., Chaves, P., Ensari, A. (eds) Pathology of the Gastrointestinal Tract. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-40560-5_1654
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DOI: https://doi.org/10.1007/978-3-319-40560-5_1654
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Publisher Name: Springer, Cham
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