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Intramuscular/Intermuscular Lipoma

  • Living reference work entry
  • First Online:
Encyclopedia of Pathology

Part of the book series: Encyclopedia of Pathology ((EP))

  • 19 Accesses

Synonyms

Infiltrative lipoma; Invasive lipoma

Definition

A benign tumor of mature adipocytes within (intramuscular) or between (intermuscular) skeletal muscles.

Clinical Features

  • Incidence

    Lipoma is the most common soft tissue tumor in the adulthood accounting for about one half of all soft tissue tumors (Myhre-Jensen 1981; Rydholm and Berg 1983). However, its real incidence may be underestimated. The frequency of lipoma seems to be higher in the obese population. Intramuscular/intermuscular lipoma accounts for less than 10% of all benign lipomas.

  • Age

    Intramuscular/intermuscular lipoma more frequently affects middle aged adults (usually between the fourth and sixth decades).

  • Sex

    There is a male predominance.

  • Site

    Intramuscular/intermuscular lipoma usually affects the large muscles of the thigh, shoulder, arm, and trunk.

  • Treatment

    Simple excision is the recommended treatment.

  • Outcome

    Intramuscular/intermuscular lipoma is benign with no capacity to dedifferentiate or metastasize....

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References

  • Dionne, G. P., & Seemayer, T. A. (1974). Infiltrating lipomas and angiolipomas revisited. Cancer, 33, 732–738.

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  • Kindblom, L. G., Angervall, L., Stener, B., & Wickbom, I. (1974). Intermuscular and intramuscular lipomas and hibernomas. A clinical, roentgenologic, histologic, and prognostic study of 46 cases. Cancer, 33, 754–762.

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  • Myhre-Jensen, O. (1981). A consecutive 7-year series of 1331 benign soft tissue tumours: Clinicopathologic data. Comparison with sarcomas. Acta Orthopaedica Scandinavica, 52, 287–293.

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  • Petit, M. M., Mols, R., Schoenmakers, E. F., Mandahl, N., & Van de Ven, W. J. (1996). LPP, the preferred fusion partner gene of HMGICin lipomas, is a novel member of the LIM protein gene family. Genomics, 36, 118–129.

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  • Rydholm, A., & Berg, N. O. (1983). Size, site and clinical incidence of lipoma: Factors in the differential diagnosis of lipoma and sarcoma. Acta Orthopaedica Scandinavica, 54, 929–934.

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  • Schoenmakers, E. F., Wanschura, S., Mols, R., Bullerdiek, J., Van den Berghe, H., & Van de Ven, W. J. (1995). Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours. Nature Genetics, 10, 436.

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  • Willén, H., Ã…kerman, M., Dal Cin, P., De Wever, I., Fletcher, C. D., Mandahl, N., et al. (1998). Comparison of chromosomal patterns with clinical features in 165 lipomas: A report of the CHAMP study group. Cancer Genetics and Cytogenetics, 102, 46–49.

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Author information

Authors and Affiliations

  1. Padua University Hospital, Padua, VE, Italy

    Rocco Cappellesso

Authors
  1. Rocco Cappellesso
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Corresponding author

Correspondence to Rocco Cappellesso .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Cappellesso, R. (2020). Intramuscular/Intermuscular Lipoma. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_5406-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_5406-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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