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Encyclopedia of Pathology pp 1–2Cite as

Postsurgical Necrobiotic Granuloma of Urinary Bladder

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Part of the book series: Encyclopedia of Pathology ((EP))

Synonyms

Necrotizing granulomatous inflammation; Necrotizing palisading granuloma; Noninfectious necrotizing granuloma

Definition

Lesion composed of spindle and epithelioid histiocytes arranged in a palisaded pattern with central necrosis, in which multinucleated giant cells are also present.

Clinical Features

  • Incidence

    It is a common finding in bladders following transurethral tumor resection.

  • Age

    Fifth to sixth decade

  • Sex

    Male preponderance

  • Site

    Common in bladders following transurethral bladder resections of urothelial carcinoma (Spagnolo and Waring 1986; Eble and Banks 1990)

    Most cases reported in the prostate follow transurethral resection of the prostate due to benign prostatic hyperplasia (Eyre et al. 1986). This type of granulomas is, therefore, rare, in other genitourinary locations.

  • Treatment

    The lesion when properly diagnosed microscopically does not require treatment.

  • Outcome

    Benign

Macroscopy

Lesions measuring 0.5–2 cm, single or multiple

Microscopy

It shows of a central...

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References and Further Reading

  • Eble, J. N., & Banks, E. R. (1990). Post-surgical necrobiotic granulomas of urinary bladder. Urology, 35, 454–457.

    Article  CAS  Google Scholar 

  • Eyre, R. C., Aaronson, A. G., & Weinstein, B. J. (1986). Palisading granulomas of the prostate associated with prior prostatic surgery. The Journal of Urology, 136, 121–122.

    Article  CAS  Google Scholar 

  • Spagnolo, D. V., & Waring, P. M. (1986). Bladder granulomata after bladder surgery. American Journal of Clinical Pathology, 86, 430–437.

    Article  CAS  Google Scholar 

  • Yamada, Y. (1986). Focal palisading granuloma in the prostate and bladder: A clinicopathologic study of 88 total cystectomy specimens. Acta Pathologica Japonica, 36, 1813–1822.

    CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Pathology Service, Champalimaud Clinical Center, Lisbon, Portugal

    Antonio Galzerano & Antonio Lopez-Beltran

  2. Department of Surgery and Pathology, University of Cordoba Medical School, Cordoba, Spain

    Antonio Lopez-Beltran

  3. Histopathology and Molecular Diagnostics, University Hospital Careggi, Florence, Italy

    Maria Rosaria Raspollini

Authors
  1. Antonio Galzerano
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  2. Antonio Lopez-Beltran
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  3. Maria Rosaria Raspollini
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Corresponding author

Correspondence to Maria Rosaria Raspollini .

Editor information

Editors and Affiliations

  1. NIJMEGEN, The Netherlands

    J.H.J.M. van Krieken

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Cite this entry

Galzerano, A., Lopez-Beltran, A., Raspollini, M.R. (2019). Postsurgical Necrobiotic Granuloma of Urinary Bladder. In: van Krieken, J. (eds) Encyclopedia of Pathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-319-28845-1_4899-1

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  • DOI: https://doi.org/10.1007/978-3-319-28845-1_4899-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-28845-1

  • Online ISBN: 978-3-319-28845-1

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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