Definition
A rare mesenchymal tumor characterized by hemangiopericytomatous pattern
Clinical Features
Incidence
Intrarenal solitary fibrous tumor is a rare neoplasm.
Age
It usually arises in middle-aged adults.
Sex
There is no gender predominance.
Site
There is no site predilection.
Treatment
The complete surgical resection is the first choice of therapy if feasible.
Outcome
Intrarenal solitary fibrous tumor shows an indolent behavior. However, aggressive cases have been reported (Hsieh et al. 2011).
Macroscopy
Well-circumscribed solitary mass with white, firm cut surface
Microscopy
The histologic appearance is the same as the pleural tumor, characterized by spindle cells with bland nuclear feature without a specific pattern, thick bands of collagen, and prominent branching and hyalinized vessels (Fig. 1) (Kuroda et al. 2014; Wang et al. 2001).
An hypercellular area of a solitary fibrous tumor of the kidney. Note the prominent branching of...
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References and Further Reading
Hsieh, T.-Y., Chang Chien, Y.-C., Chen, W.-H., et al. (2011). De novo malignant solitary fibrous tumor of the kidney. Diagnostic Pathology, 6, 96.
Kuroda, N., Ohe, C., Sakaida, N., et al. (2014). Solitary fibrous tumor of the kidney with focus on clinical and pathobiological aspects. International Journal of Clinical and Experimental Pathology, 7, 2737–2742.
Saeed, O., Zhang, S., Cheng, L., et al. (2019). STAT6 expression in solitary fibrous tumor and histologic mimics: A single institution experience. Applied Immunohistochemistry & Molecular Morphology. https://doi.org/10.1097/PAI.0000000000000745. [Epub ahead of print].
Wang, J., Arber, D. A., Frankel, K., et al. (2001). Large solitary fibrous tumor of the kidney report of two cases and review of the literature. The American Journal of Surgical Pathology, 25, 1194–1199.
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Caliò, A., Segala, D., Martignoni, G. (2020). Solitary Fibrous Tumor of the Kidney. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_4940
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DOI: https://doi.org/10.1007/978-3-030-41894-6_4940
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