Synonyms
Inverted Papilloma
Definition
Inverted papilloma is a benign urothelial neoplasm that displays an anastomosing inverted growth pattern with absent to minimal cytologic atypia.
Clinical Features
Incidence
Inverted papillomas account for <1% of all bladder urothelial neoplasms. Most tumors are usually solitary but can be multifocal. The incidence of multifocality ranges from 1.3% to 4.4% (Sung et al. 2006; Hodges et al. 2011). Tumors are typically small, with a mean size of 12.8 mm and a common range of 1–50 mm, but rarely, tumors can be as large as 8 cm (Sung et al. 2006).
Age
Most patients are usually in their sixth or seventh decade of life.
Sex
Tumors are typically more common in males; male-to-female ratio is 7:1.
Site
Inverted papillomas are most commonly found in the trigone (41% of cases) followed by the lateral wall, and posterior wall. Less commonly they also occur in the upper urothelial tract and urethra.
Treatment
Complete transurethral resection is the most...
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Araneta, R., Raspollini, M.R., Lopez-Beltran, A., Montironi, R., Cheng, L. (2020). Inverted Urothelial Papilloma. In: Raspollini, M.R., Lopez-Beltran, A. (eds) Uropathology. Encyclopedia of Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-41894-6_4833
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DOI: https://doi.org/10.1007/978-3-030-41894-6_4833
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