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Changing Definition of Immunosuppression: Targeted Therapies and Resulting Emerging Infections and Their Prevention

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Emerging Transplant Infections

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Abstract

While some biologicals have been routinely used in solid organ and hematopoietic stem cell transplant patients for years, a number of newer compounds have been added to the armamentarium for varying indications spanning from the underlying disease to complications of transplantation. This chapter aims at describing the infectious risk of a selection of compounds. The specific chapters list a number of recommendations to consider for infection prevention, in addition to the standard preventive measures in place. Given the nature of the available data, these suggestions are meant to be neither exhaustive nor mandatory and must be applied in the context of the individual patient.

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Authors and Affiliations

  1. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zürich, Zürich, Switzerland

    Nicolas J. Mueller

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  1. Nicolas J. Mueller
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Correspondence to Nicolas J. Mueller .

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Editors and Affiliations

  1. Miller School of Medicine, University of Miami, Miami, FL, USA

    Michele I. Morris

  2. Massachusetts General Hospital, Harvard University, Boston, MA, USA

    Camille Nelson Kotton

  3. Duke University, Durham, NC, USA

    Camille Wolfe

Section Editor information

  1. Infectious Diseases Division, Harvard University Medical School, Boston, MA, USA

    Camille Nelson Kotton

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Mueller, N.J. (2020). Changing Definition of Immunosuppression: Targeted Therapies and Resulting Emerging Infections and Their Prevention. In: Morris, M., Kotton, C., Wolfe, C. (eds) Emerging Transplant Infections. Springer, Cham. https://doi.org/10.1007/978-3-030-01751-4_13-1

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  • DOI: https://doi.org/10.1007/978-3-030-01751-4_13-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-01751-4

  • Online ISBN: 978-3-030-01751-4

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