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IKAROS (IKZF1) Deficiency

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Encyclopedia of Medical Immunology

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References

  • Bogaert DJ, Kuehn HS, Bonroy C, Calvo KR, Dehoorne J, Vanlander AV, Bruyne MD, Cytlak U, Bigley V, Baets FD, et al. A novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B-cell maturation defects. J Allergy Clin Immunol. 2018;141:432–435.e7.

    Article  CAS  PubMed  Google Scholar 

  • Heizmann B, Kastner P, Chan S. The Ikaros family in lymphocyte development. Curr Opin Immunol. 2018;51:14–23.

    Article  CAS  PubMed  Google Scholar 

  • Hoshino A, Okada S, Yoshida K, Nishida N, Okuno Y, Ueno H, Yamashita M, Okano T, Tsumura M, Nishimura S, et al. Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations. J Allergy Clin Immunol. 2017;140:223–31.

    Article  CAS  PubMed  Google Scholar 

  • Kuehn HS, Boisson B, Cunningham-Rundles C, Reichenbach J, Stray-Pedersen A, Gelfand EW, Maffucci P, Pierce KR, Abbott JK, Voelkerding KV, et al. Loss of B cells in patients with heterozygous mutations in IKAROS. N Engl J Med. 2016;374: 1032–43.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Yoshida N, Sakaguchi H, Muramatsu H, Okuno Y, Song C, Dovat S, Shimada A, Ozeki M, Ohnishi H, Teramoto T, et al. Germline IKAROS mutation associated with primary immunodeficiency that progressed to T-cell acute lymphoblastic leukemia. Leukemia. 2017;31:1221–3.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Pathology, University of Utah, Salt Lake City, UT, USA

    Attila Kumánovics

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  1. Attila Kumánovics
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Correspondence to Attila Kumánovics .

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Editors and Affiliations

  1. Molecular Biology, Monash University Dept. Biochemistry &, Clayton, VIC, Australia

    Ian MacKay

  2. Autoimmune Disease Research Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA

    Noel R. Rose

Section Editor information

  1. USF Health, Tampa, Florida, USA

    Jolan Walter

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Kumánovics, A. (2018). IKAROS (IKZF1) Deficiency. In: MacKay, I., Rose, N. (eds) Encyclopedia of Medical Immunology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9209-2_173-1

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  • DOI: https://doi.org/10.1007/978-1-4614-9209-2_173-1

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-9209-2

  • Online ISBN: 978-1-4614-9209-2

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