Table of contents

  1. Front Matter
    Pages i-xxi
  2. Kartik Sunagar, Nicholas R. Casewell, Sandeep Varma, Rohan Kolla, Agostinho Antunes, Yehu Moran
    Pages 1-27
  3. Kyle J. Shaney, Daren C. Card, Drew R. Schield, Robert P. Ruggiero, David D. Pollock, Stephen P. Mackessy et al.
    Pages 29-49
  4. Cassandra M. Modahl, Anthony J. Saviola, Stephen P. Mackessy
    Pages 51-79
  5. Adolfo Borges, Matthew R. Graham
    Pages 81-104
  6. Mohamed A. Abdel-Rahman, Veronica Quintero-Hernández, Lourival D. Possani
    Pages 105-124
  7. Daniele Chaves-Moreira, Dilza Trevisan-Silva, Luiza Helena Gremski, Silvio Sanches Veiga
    Pages 125-147
  8. Eduardo Gonçalves Paterson Fox
    Pages 149-167
  9. Camilla M. Whittington, Katherine Belov
    Pages 169-183
  10. M. A. Coronado, F. R. de Moraes, A. Ullah, R. Masood, V. S. Santana, R. Mariutti et al.
    Pages 239-267
  11. Alexandre Keiji Tashima, André Zelanis
    Pages 317-331
  12. Richard Hemmi Valente, Carolina Alves Nicolau, Jonas Perales, Ana Gisele da Costa Neves-Ferreira
    Pages 333-365
  13. Rafael Donadelli Melani, Livia Goto-Silva, Fábio César Sousa Nogueira, Magno Junqueira, Gilberto Barbosa Domont
    Pages 367-380
  14. Bhadrapura Lakkappa Dhananjaya, Cletus J. M. D’Souza
    Pages 381-392
  15. Francis S. Markland, Stephen D. Swenson
    Pages 393-424

About this book

Introduction

This volume provides the reader with recent advances in the fields of molecular toxinology, the biotechnological applications of venom toxins, and antivenom production. The content of the twenty chapters of Venom Genomics and Proteomics illustrates not only the enormous progress made since the implementation of omics technologies in the field of toxinology, but one also realizes the road still ahead to reach a holistic view of venomous systems. Advancement in high-throughput technologies in the field of venomics has resulted in the ability to generate comprehensive venom profiles for many species. However, research on snake genomes is still in its infancy, although such studies are eagerly awaited to gain insights into the evolutionary history of snake venom proteins, including the mechanisms that originated venom and the regulation of toxin expression. Fortunately, this objective is also at the reach of current omic technologies. Therefore it would not be unrealistic to predict a bright near future to the field of molecular toxinology.

Venom Genomics and Proteomics covers research into the venom of scaled reptiles (lizards and snakes), scorpions, spiders, ants and platypuses. Special consideration is given to a number of observations made in the area of snake venom and in the application of advanced genomics and proteomics techniques on a variety of venom samples. The final chapters give some insight into the potential clinical uses of venom derivatives and into the importance and challenges faced in the production and quality control of antivenoms.

 

Keywords

Drug Development Drug Discovery Toxin Toxinology Venom

Editors and affiliations

  • P. Gopalakrishnakone
    • 1
  • Juan J. Calvete
    • 2
  1. 1.Venom and Toxin Research Programme, Department of AnatomyYong Loo Lin School of Medicine, National University of SingaporeSingaporeSingapore
  2. 2.Structural and Functional Venomics LabInstituto de Biomedicina de Valencia (CSIC)ValenciaSpain

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-007-6416-3
  • Copyright Information Springer Science+Business Media Dordrecht 2016
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-94-007-6415-6
  • Online ISBN 978-94-007-6416-3
  • About this book
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