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Drug Design

Methodology, Concepts, and Mode-of-Action

  • Reference work
  • © 2013

Overview

  • Unique reference work on the subject of drug design
  • Full colours throughout
  • Intelligibly written and illustrated containing over 100 computer graphics
  • Including an index of about 5,000 items

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Table of contents (32 entries)

  1. Part I Fundamentals in Drug Research

  2. Part II The Search for the Lead Structure

  3. Part III Experimental and Theoretical Methods

Keywords

About this book

Unique work on structure-based drug design, covering multiple aspects of drug discovery and development. Fully colored, many images, computer animations of 3D structures (these only in electronic form). Makes the spatial aspects of interacting molecules clear to the reader, covers multiple applications and methods in drug design. Structures by mode of action, no therapeutic areas. Of high relevance for academia and industrial research. Focus on gene technology in drug design, omics-technologies computational methods experimental techniques of structure determination multiple examples on mode of action of current drugs, ADME-tox properties in drug development, QSAR methods, combinatorial chemistry, biologicals, ribosome, targeting protein-protein interfaces.

Editors and Affiliations

  • Institute of Pharmaceutical Chemistry, Philipps-University Marburg, Marburg, Germany

    Gerhard Klebe

About the editor

Well-known author has won a prize for the German edition of this work.

Bibliographic Information

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