Characteristics and Value of Machine Learning for Imaging in High Content Screening

  • Juergen A. Klenk
Part of the Methods in Molecular Biology book series (MIMB, volume 356)


Requirements for a flexible image analysis package for high content screening (HCS) are discussed. An overview of tools and techniques for image analysis and machine learning is given. Machine learning for classification and segmentation, the two fundamental elements of image analysis, is discussed. Next generation image analysis packages for HCS are reviewed. Recommendations for the development of image analysis solutions for advanced assays are given.

Key Words

Classification computer vision high content screening (HCS) image analysis machine learning morphology operations neural networks segmentation semantic networks thresholding training 


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Copyright information

© Humana Press, Inc. 2007

Authors and Affiliations

  • Juergen A. Klenk
    • 1
  1. 1.Booz Allen Hamilton, Inc.McLean

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