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Target Discovery and Validation in Pancreatic Cancer

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Target Discovery and Validation Reviews and Protocols

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 360))

Summary

Pancreatic cancer is a lethal disease and rational strategies fo gene expression, and mass spectrometric analysis of proteins, have led to identification of cellular targets with considerable potential for clinical application and patient care. These studies underscore the importance of pursuing large-scale profiling of human cancers not only for furthering our understanding of the pathogenesis of these malignancies but also for developing strategies to improve patient outcomes.

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Acknowledgments

A.M. is supported by an American Association for Cancer Research-PanCAN Career Development Award, the Lustgarten Foundation for Pancreatic Cancer Research, and National Cancer Institute R01CA113669.

Author information

Authors and Affiliations

  1. Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD

    Robert M. Beaty

  2. McKusick-Nathans Institute of Genetic Medicine, University of Southern Denmark, Odense, Denmark

    Mads Gronborg

  3. Departments of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark

    Mads Gronborg

  4. Departments of Pathology and Oncology, The Sol Goldman Pancreatic Cancer Research Center and McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD

    Jonathan R. Pollack & Anirban Maitra

Authors
  1. Robert M. Beaty
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  2. Mads Gronborg
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  3. Jonathan R. Pollack
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  4. Anirban Maitra
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Editor information

Editors and Affiliations

  1. Department of Immunology, Institute for Cancer Research, The Norwegian Radium Hospital, University of Oslo, Oslo, Norway

    Mouldy Sioud

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© 2007 Humana Press Inc.

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Beaty, R.M., Gronborg, M., Pollack, J.R., Maitra, A. (2007). Target Discovery and Validation in Pancreatic Cancer. In: Sioud, M. (eds) Target Discovery and Validation Reviews and Protocols. Methods in Molecular Biology™, vol 360. Humana Press. https://doi.org/10.1385/1-59745-165-7:57

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  • DOI: https://doi.org/10.1385/1-59745-165-7:57

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-656-6

  • Online ISBN: 978-1-59745-165-9

  • eBook Packages: Springer Protocols

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