Fabrication of Micromachined Magnetic Particle Separators for Bioseparation in Microfluidic Systems

  • Jin-Woo Choi
Part of the Methods In Molecular Biology™ book series (MIMB, volume 321)


Fabrication of micromachined magnetic particle separators is introduced with an emphasis on magnetic particle-based bioseparation in microfluidic systems. The most attractive aspect of the magnetic separation technique in biochemistry and biotechnology is ease of manipulation of biomolecules, which are immobilized on magnetic particles. Embedded electromagnets in the microfluidic channel are described for on-chip magnetic particle separation for lab-on-a-chip applications. An example of microfluidic systems with a magnetic particle separator and integrated microfluidic components is also presented for rapid magnetic particle-based bioseparation and immunoassay.

Key Words

Bioseparation magnetic particle microfluidic system microfabrication superparamagnetic particle 


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Copyright information

© Humana Press Inc. 2006

Authors and Affiliations

  • Jin-Woo Choi
    • 1
  1. 1.Department of Electrical EngineeringLouisiana State UniversityBaton Rouge

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