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An Introduction to Planar Chromatography

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Natural Products Isolation

Part of the book series: Methods in Biotechnology ((MIBT,volume 20))

Summary

Thin-layer chromatography (TLC) is an easy, cheap, rapid, and widely used method for the analysis and isolation of natural and synthetic products. It has use also in the biological evaluation of organic compounds, particularly in the areas of antimicrobial and antioxidant metabolites, and for the determination of acetylcholine esterase inhibitors that are utilized in the treatment of Alzheimer’s disease. This chapter deals with the basic principles of TLC and describes methods for the analysis and isolation of natural products. Examples of methods for isolation of several classes of natural product are detailed, and protocols for TLC bioassays are given.

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Suggested Readings

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Author information

Authors and Affiliations

  1. Centre for Pharmacognosy and Phytotherapy, The School of Pharmacy, University of London, London, UK

    Simon Gibbons

Authors
  1. Simon Gibbons
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Editor information

Editors and Affiliations

  1. Pharmaceutical Biotechnology Research Group school of Biomedical Sciences, University of Ulster at Coleraine, Coleraine, Northern Ireland, UK

    Satyajit D. Sarker

  2. Molecular Nature Limited Plas Gogerddan, Aberystwyth, Wales, UK

    Zahid Latif

  3. Phytochemistry Research Lab Department of Pharmaceutical Sciences, University of Strathclyde, Glasgow, Scotland, UK

    Alexander I. Gray

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© 2006 Humana Press Inc., Totowa,NJ

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Gibbons, S. (2006). An Introduction to Planar Chromatography. In: Sarker, S.D., Latif, Z., Gray, A.I. (eds) Natural Products Isolation. Methods in Biotechnology, vol 20. Humana Press. https://doi.org/10.1385/1-59259-955-9:77

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  • DOI: https://doi.org/10.1385/1-59259-955-9:77

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-447-0

  • Online ISBN: 978-1-59259-955-4

  • eBook Packages: Springer Protocols

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