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Amplification Refractory Mutation System and Molecular Diagnostics

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Medical Biomethods Handbook

Part of the book series: Springer Protocols Handbooks ((SPH))

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Abstract

Allele-specific polymerase chain reaction (PCR) was first described in 1989, with variations arising over the next few years such as allele-specific oligonucleotide PCR, mutant-allele-specific amplification (MASA), PCR amplification of specific alleles (PASA), and the amplification refractory mutation system (ARMS) (1–5). For convenience, the term ARMS will be used here when referring to them collectively.

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Authors and Affiliations

  1. Department of Laboratory Medicine and Pathobiology, Sunnybrook and Women’s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada

    Richard Kitching & Arun Seth

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  1. Richard Kitching
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  2. Arun Seth
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Editors and Affiliations

  1. University of Hertfordshire, Hatfield, UK

    John M. Walker  & Ralph Rapley  & 

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© 2005 Humana Press Inc., Totowa, NJ

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Kitching, R., Seth, A. (2005). Amplification Refractory Mutation System and Molecular Diagnostics. In: Walker, J.M., Rapley, R. (eds) Medical Biomethods Handbook. Springer Protocols Handbooks. Humana Press. https://doi.org/10.1385/1-59259-870-6:155

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  • DOI: https://doi.org/10.1385/1-59259-870-6:155

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-288-9

  • Online ISBN: 978-1-59259-870-0

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