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SNP Typing in Forensic Genetics

A Review

  • Protocol
Forensic DNA Typing Protocols

Part of the book series: Methods in Molecular Biology ((MIMB,volume 297))

Abstract

Single nucleotide polymorphisms (SNPs) are emerging as new markers of interest to the forensic community because of their abundance in the human genome, their low mutation rate, the opportunity they present of analyzing smaller fragments of deoxyribonucleic acid (DNA) than with short tandem repeats-important in degraded DNA samples-and the possibility of automating the analysis with high-throughput technologies. Many new technologies for genotyping SNPs have been developed in the past few years. We describe the principles of the allelic discrimination reactions and the technologies used for each of them. The aim of this chapter is to help in the understanding of the methodologies used in SNP genotyping and in the selection of the most appropriate techniques for forensic purposes.

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Authors and Affiliations

  1. Institute of Legal Medicine, Faculty of Medicine, University of Santiago de Compostela, Santiago de Compostela, Galicia, Spain

    Beatriz Sobrino & Angel Carracedo

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  1. Beatriz Sobrino
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  2. Angel Carracedo
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  1. Institute of Legal Medicine, University of Santiago de Compostela, Galicia, Spain

    Angel Carracedo

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© 2005 Humana Press Inc., Totowa, NJ

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Sobrino, B., Carracedo, A. (2005). SNP Typing in Forensic Genetics. In: Carracedo, A. (eds) Forensic DNA Typing Protocols. Methods in Molecular Biology, vol 297. Humana Press. https://doi.org/10.1385/1-59259-867-6:107

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  • DOI: https://doi.org/10.1385/1-59259-867-6:107

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-264-3

  • Online ISBN: 978-1-59259-867-0

  • eBook Packages: Springer Protocols

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