Abstract
The cyclin/cyclin-dependent kinase (Cdk) complexes and the Cdk inhibitors (CDKI) are crucial regulators of cell cycle progression in all eukaryotic cells. Using rat cardiac myocytes as a model system, this chapter provides a detailed account of methods that can be employed to measure both cyclin/Cdk activity in cells and the extent of CDKI inhibitory activity present in a particular cell type.
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Brooks, G. (2005). Cyclins, Cyclin-Dependent Kinases, and Cyclin-Dependent Kinase Inhibitors. In: Humphrey, T., Brooks, G. (eds) Cell Cycle Control. Methods in Molecular Biology™, vol 296. Humana Press. https://doi.org/10.1385/1-59259-857-9:291
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DOI: https://doi.org/10.1385/1-59259-857-9:291
Publisher Name: Humana Press
Print ISBN: 978-1-58829-144-8
Online ISBN: 978-1-59259-857-1
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