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Cell Cycle Control pp 113–153Cite as

The Mammalian Cell Cycle

An Overview

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Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 296))

Abstract

In recent years, we have witnessed major advances in our understanding of the mammalian cell cycle and how it is regulated. Normal mammalian cellular proliferation is tightly regulated at each phase of the cell cycle by the activation and deactivation of a series of proteins that constitute the cell cycle machinery. This review article describes the various phases of the mammalian cell cycle and focuses on the cell cycle regulatory molecules that act at each stage to ensure normal cellular progression.

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Authors
  1. Jane V. Harper
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  2. Gavin Brooks
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Editors and Affiliations

  1. MRC Radiation and Genome Stability Unit, Harwell, Didcot, UK

    Tim Humphrey

  2. School of Pharmacy, University of Reading Whiteknights, Reading, UK

    Gavin Brooks

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Harper, J.V., Brooks, G. (2005). The Mammalian Cell Cycle. In: Humphrey, T., Brooks, G. (eds) Cell Cycle Control. Methods in Molecular Biology™, vol 296. Humana Press. https://doi.org/10.1385/1-59259-857-9:113

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  • DOI: https://doi.org/10.1385/1-59259-857-9:113

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-144-8

  • Online ISBN: 978-1-59259-857-1

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