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A Historical Perspective on RNA Editing

How the Peculiar and Bizarre Became Mainstream
Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 265)

Abstract

The known examples of RNA editing now encompass a variety of alterations of RNA primary sequence that arise from base modifications, nucleotide insertions or deletions, and nucleotide replacements. Hence, the definition of RNA editing has evolved as new systems have been described. This chapter presents a historical perspective on some of the pivotal discoveries that helped direct the current avenues of research in the field of RNA editing.

Key Words

RNA editing RNA processing deaminase trypanosomes plastids 

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Copyright information

© Humana Press Inc. 2004

Authors and Affiliations

  1. 1.Department of Microbiology and Molecular GeneticsMichigan State UniversityEast Lansing

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