PCR Diagnosis of T-Cell Lymphoma in Paraffin-Embedded Bone Marrow Biopsies

  • Jean Benhattar
  • Sandra Gebhard
Part of the Methods in Molecular Medicine book series (MIMM, volume 97)

Abstract

Management of T-cell lymphoma patients requires bone marrow examination for the assessment of stage and prognosis (1,2). Bone marrow biopsy (BMB) is mandatory when bone marrow aspirate is not successful (e.g., in cases of patchy lymphomatous infiltration or induction of fibrosis [“dry aspirate”]) (3). Moreover, BMB has some advantages over aspirate, such as examination of a greater volume of tissue with preserved architecture, assessment of cellularity, and application of immunohistochemistry.

Keywords

Vortex Formaldehyde Migration Mercury Lymphoma 

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Copyright information

© Humana Press Inc., Totowa, NJ 2004

Authors and Affiliations

  • Jean Benhattar
    • 1
  • Sandra Gebhard
    • 1
  1. 1.Institute of PathologyCHUVLausanneSwitzerland

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