Abstract
Infectious diseases result in significant morbidity and mortality worldwide. Preventing these infections is both a public health priority and the primary goal of vaccine research. The discovery that cell-mediated and/or humoral immune responses against viruses, parasites, bacteria and tumor antigens can be induced by antigen-encoding DNA plasmids is revolutionizing the vaccine development field (1–3). DNA vaccines (also known as plasmid DNA or nucleic acid vaccines) have been proven to successfully prevent infection in a variety of animal models, and are currently undergoing clinical trials in humans for the prevention of a variety of infections, including HIV (1,4,5).
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© 2000 Humana Press Inc., Totowa, NJ
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Mor, G., Eliza, M. (2000). DNA Vaccination. In: Lowrie, D.B., Whalen, R.G. (eds) DNA Vaccines. Methods in Molecular Medicine™, vol 29. Humana Press. https://doi.org/10.1385/1-59259-688-6:489
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DOI: https://doi.org/10.1385/1-59259-688-6:489
Publisher Name: Humana Press
Print ISBN: 978-0-89603-580-5
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