Abstract
The ability of oligonucleotides to bind double-stranded DNA in a sequence specific manner, forming a DNA triple helix structure, has led to a number of novel approaches in the study of various structural and functional properties of DNA in vitro and in vivo including transcription inhibition (1–3), site-directed mutagenesis (4) and detection of DNA polymorphism (5).
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References
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© 2000 Humana Press Inc., Totowa, NJ
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Kochetkova, M., Shannon, M.F. (2000). Triplex-Forming Oligonucleotides and Their Use in the Analysis of Gene Transcription. In: Tymms, M.J. (eds) Transcription Factor Protocols. Methods in Molecular Biology™, vol 130. Humana Press. https://doi.org/10.1385/1-59259-686-X:189
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DOI: https://doi.org/10.1385/1-59259-686-X:189
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Online ISBN: 978-1-59259-686-7
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