Abstract
Embryonic skeletal muscles originate from metameric mesodermal structures called somites, which are formed according to a craniocaudal gradient from the paraxial mesoderm. In addition to providing all of the striated musculature of the body, somites give rise to the dorsal dermis and the axial skeleton. In birds, microsurgical experiments have been performed on newly formed somites to study their derivatives (1,2). It has been demonstrated that the somite contains a dorsal compartment providing the dermomyotome from which striated muscle and dermis originate and a ventral compartment forming the sclerotome from which the axial skeleton develops (for review, see ref. 3).
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References
Chevallier, A., Kieny, M., and Mauger A. (1977) Limb-somite relationship: Origin of the limb musculature. J. Embryol. Exp. Morphol. 41, 245–258.
Christ, B., Jacob, H., and Jacob, M. (1978) On the formation of the myotomes in avian embryos. An experimental and scanning electron microscope study. Experientia 34, 514–516.
Christ, B. and Ordhal, C. (1995) Early stages of chick somite development. Anat. Embryol. 191, 381–396.
Fredette, B. J., and Landmesser, L. T. (1991) A reevaluation of the role of innervation in primary and secondary myogenesis in developing chick muscle. Dev. Biol. 143, 19–33.
Wilson, S. J. and Harris, A. J. (1993) Formation of myotubes in aneural rat muscles. Dev. Biol. 156, 509–518.
Ashby, P. R., Pinçon Raymond, M., and Harris, A. J. (1993) Regulation of myogenesis in paralyzed muscles in the mouse mutants peroneal-muscular-atrophy and muscular-dysgenesis. Dev. Biol. 156, 2, 529–536.
Fontaine-Pérus, J., Jarno, V., Fournier le Ray, C., Li, Z., and Paulin, D. (1995) Mouse chick chimera: A new model to study the in ovo developmental potentialities of mammalian somites. Development 121, 1705–1718.
Auda-Boucher, G., Jarno, V., Fournier-Thibault, C., Butler-Browne, G., and Fontaine-Pérus, J. (1997) Acetylcholine receptor formation in mouse-chick chimera. Exp. Cell Res. 236, 29–42.
Li, Z., Marchand, P., Babinet C., and Paulin, D. (1993) Desmin sequence elements regulating skeletal muscle-specific expression in transgenic mice. Development 117, 947–959.
Fontaine-Pérus, J., Halgand, P., Chéraud, Y., Rouaud, T., Velasco, M. E., Cifuentes Diaz, C., and Rieger, F. (1997) Mouse-chick chimera: A developmental model of murine neurogenic cells. Development 124, 3025–3036.
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© 2000 Humana Press Inc., Totowa, NJ
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Fontaine-Pérus, J. (2000). Interspecific Mouse-Chick Chimeras. In: Walker, J.M., Tuan, R.S., Lo, C.W. (eds) Developmental Biology Protocols. Methods in Molecular Biology™, vol 135. Humana Press. https://doi.org/10.1385/1-59259-685-1:443
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DOI: https://doi.org/10.1385/1-59259-685-1:443
Publisher Name: Humana Press
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