Abstract
Short (153–350 bp) DNA fragments containing single nucleosome cores have been employed for investigation of a variety of topics, including binding of regulatory transcription factors to nucleosomes (1) and mechanism of transcription of nucleosomal templates (2). The major advantage of this experimental system is relative simplicity of isolation and analysis of uniquely positioned cores.
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References
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© 1999 Humana Press Inc.
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Studitsky, V.M. (1999). Preparation and Analysis of Positioned Nucleosomes. In: Becker, P.B. (eds) Chromatin Protocols. Methods in Molecular Biology™, vol 119. Humana Press. https://doi.org/10.1385/1-59259-681-9:17
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DOI: https://doi.org/10.1385/1-59259-681-9:17
Publisher Name: Humana Press
Print ISBN: 978-0-89603-665-9
Online ISBN: 978-1-59259-681-2
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