Molecular Cytogenetic Analysis of Sperm from Infertile Males Undergoing Intracytoplasmic Sperm Injection

  • William G. Kearns
  • Myung-Geol Pang
  • Darren Griffin
  • Lesil Brihn
  • Michael Stacey
  • Gustavo F. Doncel
  • Sergio Oehninger
  • Anabil A. Acosta
  • Stanton F. Hoegerman
Part of the Methods in Molecular Biology™ book series (MIMB, volume 123)


The successful implementation of intracytoplasmic sperm injection (ICSI) has provided a unique means to allow couples suffering from severe male infertility to achieve their reproductive goals. If the infertile man has a germ cell in the ejaculate or retrievable from the reproductive tract, ICSI can be carried out with remarkable fertilization results. However, despite the great therapeutic advantages of the technique, ICSI provides solutions to clinicians often in the absence of an etiologic or pathophysiologic diagnosis.


Infertile Male Semen Parameter Nonobstructive Azoospermia Normal Sperm Morphology Diploid Sperm 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Humana Press Inc. 2000

Authors and Affiliations

  • William G. Kearns
    • 1
    • 2
  • Myung-Geol Pang
    • 3
  • Darren Griffin
    • 4
  • Lesil Brihn
    • 5
  • Michael Stacey
    • 5
  • Gustavo F. Doncel
    • 6
  • Sergio Oehninger
    • 6
  • Anabil A. Acosta
    • 7
  • Stanton F. Hoegerman
    • 8
  1. 1.Division of Medical GeneticsCenter for Pediatric ResearchNorfolk
  2. 2.The Johns Hopkins University School of MedicineBaltimore
  3. 3.Biomedical CenterKorea Advanced Institute of Science and TechnologyTaejonKorea
  4. 4.Department of Biology and BiochemistryBrunel UniversityUxbridgeUK
  5. 5.Center for Pediatric Research, Division of Medical GeneticsEastern Virginia Medical SchoolNorfolk
  6. 6.Jones Institute for Women’s HealthEastern Virginia Medical SchoolNorfolk
  7. 7.Centro de Estudios en Ginecologia y ReproduccionBuenos AiresArgentina
  8. 8.Department of BiologyThe College of William and MaryWilliamsburg

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