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Comparative Gene Mapping in Exotic Species Using FISH

  • Stephen A. Wilcox
  • Roland Toder
  • Pino Maccarone
  • Jennifer A. Marshall-Graves
Part of the Methods in Molecular Biology™ book series (MIMB, volume 123)

Abstract

Comparative genome analysis between two distantly related species allows the organization of genes to be traced from a common ancestor. When several genes are mapped in one species and these genes are then localized in the distantly related species, then the genomic content of this region can be inferred in the common ancestor. If two species are closely related in evolutionary terms, then larger blocks of the genome will be conserved. Therefore these segments can be easily traced back to a common ancestor. Such comparisons have made it possible to trace the evolutionary origins of regions of the mammalian X chromosome (1).

Keywords

Chromosome Preparation Cell Culture Flask Saline Sodium Citrate Deionized Formamide Chromosome Denaturation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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Copyright information

© Humana Press Inc. 2000

Authors and Affiliations

  • Stephen A. Wilcox
    • 1
  • Roland Toder
    • 1
  • Pino Maccarone
    • 1
  • Jennifer A. Marshall-Graves
    • 1
  1. 1.Department of Genetics and Human VariationLa Trobe UniversityBundooraAustralia

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