Abstract
The stress-activated protein kinases (SAPKs)/c-Jun N2-terminal kinases (JNKs) and the p38 mitogen-activated protein kinases (MAPKs) are two MAPK groups activated predominantly by stresses and proinflammatory stimuli. Table 1 lists some of the stimuli known to recruit both the SAPKs/JNKs and p38s. In general, the same stimuli that activate the SAPKs/JNKs will also activate the p38s. One exception is ischemia-reperfusion. In this instance, the SAPKs/JNKs are activated exclusively during reperfusion, while the p38s are activated during ischemia and remain active during reperfusion (1).
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Kyriakis, J.M., Liu, H., Chadee, D.N. (2004). Activation of SAPKs/JNKs and p38s In Vitro. In: Seger, R. (eds) MAP Kinase Signaling Protocols. Methods in Molecular Biology™, vol 250. Humana Press. https://doi.org/10.1385/1-59259-671-1:61
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DOI: https://doi.org/10.1385/1-59259-671-1:61
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