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Visualizing Apoptosis

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Book cover Drosophila Cytogenetics Protocols

Part of the book series: Methods in Molecular Biology ((MIMB,volume 247))

Abstract

Cells undergoing apoptosis display a number of morphological changes, including chromatin condensation, cytoplasmic shrinkage, membrane blebbing, and the formation of apoptotic bodies (1). These morphological changes are accompanied by structural changes within the cell, such as the reorganization of actin, nuclear lamin cleavage, fragmentation of DNA, and “flipping” of the phospholipid phosphatidylserine from the interior leaflet of the plasma membrane to the exterior of the cell (2–5).

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Author information

Authors and Affiliations

  1. Department of Biology, Boston University, Boston, MA

    Kimberly McCall, Jason S. Baum, Kristen Cullen & Jeanne S. Peterson

Authors
  1. Kimberly McCall
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  2. Jason S. Baum
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  3. Kristen Cullen
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  4. Jeanne S. Peterson
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Editor information

Editors and Affiliations

  1. Department of Pharmacological Sciences, State University of New York at Stony Brook, NY

    Daryl S. Henderson

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© 2004 Humana Press Inc., Totowa, NJ

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McCall, K., Baum, J.S., Cullen, K., Peterson, J.S. (2004). Visualizing Apoptosis. In: Henderson, D.S. (eds) Drosophila Cytogenetics Protocols. Methods in Molecular Biology, vol 247. Humana Press. https://doi.org/10.1385/1-59259-665-7:431

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  • DOI: https://doi.org/10.1385/1-59259-665-7:431

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-050-2

  • Online ISBN: 978-1-59259-665-2

  • eBook Packages: Springer Protocols

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