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Chiral Separation Principles

An Introduction

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Chiral Separations

Part of the book series: Methods in Molecular Biology ((MIMB,volume 243))

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Abstract

The development of methods for chiral separation on an analytical as well as on a preparative scale has attracted great attention during the past two decades. Chromatographic methods such as gas chromatography (GC) (1), high-performance liquid chromatography (HPLC) (2–6), supercritical fluid chromatography (SFC) (7–9), and thin-layer chromatography (TLC) (10–13) have been developed using different chiral separation principles. More recently, capillary electrophoresis (CE) (14–21) and capillary electrochromatography (CEC) (22–25) have been shown to be powerful alternatives to chromatographic methods. Several separation principles successfully used in HPLC have been transferred to CE and CEC. For the separation of enantiomers on a preparative scale, LC has become increasingly attractive.

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  1. Institute of Pharmaceutical Chemistry and Pharmaceutical Technology, Karl-Franzens University, Graz, Austria

    Gerald Gübitz & Martin G. Schmid

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  1. Gerald Gübitz
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  1. Institute of Pharmaceutical Chemistry and Pharmaceutical Technology, Karl-Franzens University, Graz, Austria

    Gerald Gübitz  & Martin G. Schmid  & 

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© 2004 Humana Press Inc.,Totowa, NJ

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Gübitz, G., Schmid, M.G. (2004). Chiral Separation Principles. In: Gübitz, G., Schmid, M.G. (eds) Chiral Separations. Methods in Molecular Biology, vol 243. Humana Press. https://doi.org/10.1385/1-59259-648-7:001

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  • DOI: https://doi.org/10.1385/1-59259-648-7:001

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-150-9

  • Online ISBN: 978-1-59259-648-5

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