How to Build Up Biosensors With the Cantilever of the Atomic Force Microscope

  • Ricardo de Souza Pereira
Part of the Methods in Molecular Biology™ book series (MIMB, volume 242)


With the advent of the atomic force microscopy (AFM), the study of biological samples has become more realistic because, in most cases, samples are not covered or fixed and this makes it possible to observe them while alive (1,2). This advantage of the AFM prompted a new invention: nanobiosensors using the cantilever (probe) of the AFM, which made possible the observation of specific molecules (including medications) as they enter or exit living cells (3,4).


Atomic Force Microscopy Immobilize Enzyme Probe Beam Gold Film Complementary Strand 
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Copyright information

© Humana Press Inc., Totowa, NJ 2004

Authors and Affiliations

  • Ricardo de Souza Pereira
    • 1
  1. 1.Institute of Biomedical SciencesSão PauloBrazil

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