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Computer Analysis of 2-D Images

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Book cover 2-D Proteome Analysis Protocols

Part of the book series: Methods in Molecular Biology ((MIMB,volume 112))

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Abstract

Two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) images, when used to analyze protein expression in large sets of biological samples, are best processed by computer. In this manner, one can detect and quantify even the faintest spots, quantitatively compare 2-D images among each other, or identify protein expression changes across various sets of 2-D images, such as disease vs control, or different stages in a toxicological study (1).

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References

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© 1999 Humana Press Inc., Totowa, NJ

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Appel, R.D., Hochstrasser, D.F. (1999). Computer Analysis of 2-D Images. In: Link, A.J. (eds) 2-D Proteome Analysis Protocols. Methods in Molecular Biology, vol 112. Humana Press. https://doi.org/10.1385/1-59259-584-7:363

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  • DOI: https://doi.org/10.1385/1-59259-584-7:363

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-524-9

  • Online ISBN: 978-1-59259-584-6

  • eBook Packages: Springer Protocols

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