Interaction of Viral Chemokine Inhibitors with Chemokines

  • Antonio Alcami
Part of the Methods in Molecular Biology™ book series (MIMB, volume 239)

Abstract

Viruses modulate the chemokine network by encoding homologs of chemokines and chemokine receptors and secreted proteins that bind chemokines (1, 2, 3). These mechanisms have been identified in large DNA viruses such as herpesviruses and poxviruses. The exceptions are the chemokinelike activity of the human immunodeficiency virus (HIV) Tat protein and the mimicry of fractalkine by the glycoprotein G of respiratory syncytial virus.

Keywords

DMSO Titration Electrophoresis Immobilization HEPES 

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Copyright information

© Humana Press Inc., Totowa, NJ 2004

Authors and Affiliations

  • Antonio Alcami
    • 1
  1. 1.Department of Medicine and Division of Virology, Department of PathologyUniversity of CambridgeCambridgeUK

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