Methodologies for Processing Biodegradable and Natural Origin Scaffolds for Bone and Cartilage Tissue-Engineering Applications

  • Manuela E. Gomes
  • Patrícia B. Malafaya
  • Rui L. Reis
Part of the Methods in Molecular Biology™ book series (MIMB, volume 238)


The ultimate goal of tissue engineering is to replace, repair or enhance the biological function of damaged, absent or dysfunctional elements of a tissue or an organ. Engineered tissues are produced by using cells that are manipulated through their extracellular environment to develop living biological substitutes for tissues that are lacking or malfunctioning (1, 2, 3, 4, 5). Many different strategies may be used to accomplish this goal. Among the most important factors that determine the selection of the best strategy for developing and utilizing engineered tissues are the technical feasibility, the required properties of the implant, and the interaction of the host with the graft.


Tissue Engineering Injection Molding Biodegradable Polymer Compression Molding Fuse Deposition Modeling 
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Copyright information

© Humana Press Inc. 2004

Authors and Affiliations

  • Manuela E. Gomes
    • 1
  • Patrícia B. Malafaya
    • 1
  • Rui L. Reis
    • 1
  1. 1.Biomaterials, Biodegradables, and Biomimetics, Department of Polymer EngineeringUniversity of MinhoBragaPortugal

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