Gas Chromatography-Mass Spectrometric Analysis of Free 3-Chlorotyrosine, 3-Bromotyrosine, Ortho-Tyrosine, and 3-Nitrotyrosine in Biological Fluids

  • Joseph P. Gaut
  • Jaeman Byun
  • Jay W. Heinecke
Part of the Methods in Pharmacology and Toxicology book series (MIPT)


Reactive oxidants are thought to protect the host by destroying invading microbes (1). However, owing to their indiscriminate nature, reactive oxidants might also damage the host if generated inappropriately. Indeed, they have been implicated in a wide array of pathologies (2, 3, 4).


Artifact Formation Internal Standard Peak Artifact Peak Chemical Ionization Mode Standard Peak Area 
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Copyright information

© Humana Press Inc.,Totowa, NJ 2003

Authors and Affiliations

  • Joseph P. Gaut
    • 1
  • Jaeman Byun
    • 1
  • Jay W. Heinecke
    • 1
  1. 1.Department of MedicineWashington University School of MedicineSt. Louis

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