Abstract
Senescence is thought to be a programmed response to protect cells from DNA damage by preventing cell cycle progression under stress conditions (1). The prolonged arrest associated with senescence limits the number of mutational hits required for tumorigenesis, supporting a role for senescence as a tumor suppressive mechanism.
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© 2004 Humana Press Inc., Totowa, NJ
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Jardine, L.J. (2004). Identification of Senescence in Cancer Cells. In: Langdon, S.P. (eds) Cancer Cell Culture. Methods in Molecular Medicine™, vol 88. Humana Press. https://doi.org/10.1385/1-59259-406-9:231
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DOI: https://doi.org/10.1385/1-59259-406-9:231
Publisher Name: Humana Press
Print ISBN: 978-1-58829-079-3
Online ISBN: 978-1-59259-406-1
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