Abstract
A key feature of malignant cells is their capacity to invade surrounding tissue and metastasize to distant sites (1,2). The process of metastasis involves a complex series of events that include cell transformation and proliferation, vascular invasion at primary growth site with associated basement membrane degradation, transport through capillary or lymphatic vessels, attachment of tumor cells to endothelial or subendothelial structures at the secondary site, and the subsequent growth of the secondary tumor mass (3).
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© 2004 Humana Press Inc., Totowa, NJ
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Scott, W.N. (2004). Invasion and Motility Assays. In: Langdon, S.P. (eds) Cancer Cell Culture. Methods in Molecular Medicine™, vol 88. Humana Press. https://doi.org/10.1385/1-59259-406-9:225
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DOI: https://doi.org/10.1385/1-59259-406-9:225
Publisher Name: Humana Press
Print ISBN: 978-1-58829-079-3
Online ISBN: 978-1-59259-406-1
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