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Receptor Knock-Out and Gene Targeting

Generation of Knock-Out Mice

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Book cover Opioid Research

Part of the book series: Methods in Molecular Biology™ ((MIMM,volume 84))

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Abstract

Until recently, opioid receptors were studied only by a pharmacological approach because agonists and antagonists were the only tools available (1). Interpretation of the experimental data was complicated because of the poor selectivity of opioid compounds. The precise contribution of each receptor to the effects of opioid drugs remained to be elucidated.

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© 2003 Humana Press Inc.

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Sora, I., Ikeda, K., Mishina, Y. (2003). Receptor Knock-Out and Gene Targeting. In: Pan, Z.Z. (eds) Opioid Research. Methods in Molecular Biology™, vol 84. Humana Press. https://doi.org/10.1385/1-59259-379-8:205

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  • DOI: https://doi.org/10.1385/1-59259-379-8:205

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-059-5

  • Online ISBN: 978-1-59259-379-8

  • eBook Packages: Springer Protocols

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