Abstract
Until recently, opioid receptors were studied only by a pharmacological approach because agonists and antagonists were the only tools available (1). Interpretation of the experimental data was complicated because of the poor selectivity of opioid compounds. The precise contribution of each receptor to the effects of opioid drugs remained to be elucidated.
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Sora, I., Ikeda, K., Mishina, Y. (2003). Receptor Knock-Out and Gene Targeting. In: Pan, Z.Z. (eds) Opioid Research. Methods in Molecular Biology™, vol 84. Humana Press. https://doi.org/10.1385/1-59259-379-8:205
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DOI: https://doi.org/10.1385/1-59259-379-8:205
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