Abstract
The widespread acceptance of prostate-specific antigen (PSA) testing by clinicians as evidence of prostatic pathology and recognition that elevated levels in serum often precede overt disease has permitted a much earlier identification of patients with prostatic epithelial changes, particularly cancer. Prostate cancer patients thus identified are very often asymptomatic with clinically benign prostates on digital rectal examination.
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Gardiner, R.A., Burger, M., Clements, J.A., Lavin, M.F. (2003). Realizing the Potential of Ejaculate/Seminal Fluid in Detecting and Predicting Natural History. In: Russell, P.J., Jackson, P., Kingsley, E.A. (eds) Prostate Cancer Methods and Protocols. Methods in Molecular Medicine™, vol 81. Springer, Totowa, NJ. https://doi.org/10.1385/1-59259-372-0:199
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