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Human Osteoblast Culture

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Bone Research Protocols

Part of the book series: Methods in Molecular Medicine ((MIMM,volume 80))

Abstract

Osteoblasts are the cells responsible for the formation of bone; they synthesize almost all of the constituents of the bone matrix and direct its subsequent mineralization. Once a phase of active bone formation is completed the osteoblasts do not become senescent but instead redifferentiate into one of two other cell types: osteocytes and bone lining cells, both of which play a major role in the regulation of calcium homeostasis and bone remodeling.

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Author information

Authors and Affiliations

  1. Department of Human Anatomy and Cell Biology, University of Liverpool, Liverpool, UK

    James A. Gallagher

Authors
  1. James A. Gallagher
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Editor information

Editors and Affiliations

  1. University of Aberdeen Medical School, Aberdeen, UK

    Miep H. Helfrich PhD  & Stuart H. Ralston MD  & 

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© 2003 Humana Press Inc., Totowa, NJ

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Gallagher, J.A. (2003). Human Osteoblast Culture. In: Helfrich, M.H., Ralston, S.H. (eds) Bone Research Protocols. Methods in Molecular Medicine, vol 80. Humana Press. https://doi.org/10.1385/1-59259-366-6:3

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  • DOI: https://doi.org/10.1385/1-59259-366-6:3

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-044-1

  • Online ISBN: 978-1-59259-366-8

  • eBook Packages: Springer Protocols

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