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Efficient Viral Gene Transfer to Rodent Hearts In Vivo

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Cardiac Cell and Gene Transfer

Part of the book series: Methods in Molecular Biology ((MIMB,volume 219))

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Abstract

Targeting genes to the heart through somatic gene transfer is allowing investigators to manipulate specific molecules and signal transduction pathways in both in vitro and in vivo models of cardiovascular disease (1,2). This approach permits us to test the role of these molecules and pathways of disease pathogenesis and progression (1).

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References

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Author information

Authors and Affiliations

  1. Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA

    Federica del Monte

  2. Cardiology Laboratory of Integrative Physiology and Imaging, Cardiovascular Research Center, Harvard Medical School, Massachusetts General Hospital, Charlestown, MA

    Roger J. Hajjar

Authors
  1. Federica del Monte
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  2. Roger J. Hajjar
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Editor information

Editors and Affiliations

  1. Department of Physiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI

    Joseph M. Metzger (Director) (Director)

  2. Center for Integrative Genomics, University of Michigan, Ann Arbor, MI

    Joseph M. Metzger (Director) (Director)

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© 2003 Humana Press Inc.

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del Monte, F., Hajjar, R.J. (2003). Efficient Viral Gene Transfer to Rodent Hearts In Vivo. In: Metzger, J.M. (eds) Cardiac Cell and Gene Transfer. Methods in Molecular Biology, vol 219. Springer, Totowa, NJ. https://doi.org/10.1385/1-59259-350-X:179

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  • DOI: https://doi.org/10.1385/1-59259-350-X:179

  • Publisher Name: Springer, Totowa, NJ

  • Print ISBN: 978-0-89603-994-0

  • Online ISBN: 978-1-59259-350-7

  • eBook Packages: Springer Protocols

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