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Psychiatric Genetics pp 23–61Cite as

Analytical Methods Applied to Psychiatric Genetics

  • Protocol

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 77))

Abstract

The development of gene-mapping methodology has not been a linear process. Instead, this development has been multidimensional, culminating in the creation of a powerful and heterogeneous collection of tools. A description of the history of the development of this would include words such as “opportunistic” (i.e., capitalizing on the newest developments in computer technology and genomics) and “problem-solving oriented” (i.e., constantly addressing issues (such as the spotted nature of linkage disequilibrium) that arose during the development of the methodology). Therefore, the following presentation is method-oriented rather than problemoriented. In describing the modern methodology of gene mapping, attempts will be made to describe the origin of a given methodology, the problems it was designed to address, and its known strengths and weaknesses.

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Author information

Authors and Affiliations

  1. Center for the Psychology of Abilities, Competencies, and Expertise (PACE), Department of Psychology, Yale University, New Haven, CT, USA

    Elena L. Grigorenko

  2. Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

    David L. Pauls

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  1. Elena L. Grigorenko
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  2. David L. Pauls
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Editors and Affiliations

  1. Hôpital Albert Chenevier, Creteil, France

    Marion Leboyer MD, PhD

  2. Hôpital Henri Mondor, Creteil, France

    Frank Bellivier MD, PhD

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Grigorenko, E.L., Pauls, D.L. (2003). Analytical Methods Applied to Psychiatric Genetics. In: Leboyer, M., Bellivier, F. (eds) Psychiatric Genetics. Methods in Molecular Medicine™, vol 77. Humana Press. https://doi.org/10.1385/1-59259-348-8:23

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  • DOI: https://doi.org/10.1385/1-59259-348-8:23

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-037-3

  • Online ISBN: 978-1-59259-348-4

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