Abstract
All cellular components of the blood originate from hematopoietic stem cells in the bone marrow. These pluripotent stem cells give rise to two lineages of specialized cells (Fig. 1). The lymphoid lineage produces B- and T-cells; the myeloid lineage gives rise to leukocytes, erythroblasts (the precursors of erythrocytes), and megakaryocytes (which produce platelets) (1).
Hematopoietic stem cell-derived lineages.
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References
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de Winther, M.P.J., Heeringa, P. (2003). Bone Marrow Transplantations to Study Gene Function in Hematopoietic Cells. In: Hofker, M.H., van Deursen, J. (eds) Transgenic Mouse. Methods in Molecular Biology™, vol 209. Humana Press. https://doi.org/10.1385/1-59259-340-2:281
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DOI: https://doi.org/10.1385/1-59259-340-2:281
Publisher Name: Humana Press
Print ISBN: 978-0-89603-915-5
Online ISBN: 978-1-59259-340-8
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