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Tumor Suppressor Genes pp 577–597Cite as

Tumor Suppressor Gene Therapy

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Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 223))

Abstract

The preceding chapters in these two volumes on tumor suppressor genes (TSG) are a comprehensive compilation of what is currently known about the structure, function, activation, and regulation of TSGs, along with the roles they play in the myriad biochemical pathways that network to result in living cells. With recent developments in molecular genetics, new information is revealed daily, and it is likely that we have only scratched the surface of the base of knowledge about TSGs that will soon be available. Even so, the studies reported thus far have already led to the identification of genetic alterations in TSGs that are responsible, in whole or in part, for cancer, and subsequently to the development and implementation of formidable therapeutic strategies.

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Author information

Authors and Affiliations

  1. Department of Thoracic and Cardiovascular Surgery, University of Texas M. D. Anderson Cancer Center, Houston, TX

    Jack A. Roth

  2. Biotechwrite: Biomedical and Science Communications, Kalamazoo, MI

    Susan F. Grammer

Authors
  1. Jack A. Roth
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  2. Susan F. Grammer
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Editor information

Editors and Affiliations

  1. Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA

    Wafik S. El-Deiry MD, PhD

  2. Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, PA

    Wafik S. El-Deiry MD, PhD

  3. Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, PA

    Wafik S. El-Deiry MD, PhD

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© 2003 Humana Press Inc.

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Roth, J.A., Grammer, S.F. (2003). Tumor Suppressor Gene Therapy. In: El-Deiry, W.S. (eds) Tumor Suppressor Genes. Methods in Molecular Biology™, vol 223. Humana Press. https://doi.org/10.1385/1-59259-329-1:577

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  • DOI: https://doi.org/10.1385/1-59259-329-1:577

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-987-2

  • Online ISBN: 978-1-59259-329-3

  • eBook Packages: Springer Protocols

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