Tumor Suppressor Gene Therapy

  • Jack A. Roth
  • Susan F. Grammer
Part of the Methods in Molecular Biology™ book series (MIMB, volume 223)


The preceding chapters in these two volumes on tumor suppressor genes (TSG) are a comprehensive compilation of what is currently known about the structure, function, activation, and regulation of TSGs, along with the roles they play in the myriad biochemical pathways that network to result in living cells. With recent developments in molecular genetics, new information is revealed daily, and it is likely that we have only scratched the surface of the base of knowledge about TSGs that will soon be available. Even so, the studies reported thus far have already led to the identification of genetic alterations in TSGs that are responsible, in whole or in part, for cancer, and subsequently to the development and implementation of formidable therapeutic strategies.


Gene Therapy Gene Therapy Strategy Gene Therapy Protocol Gene Therapy Clinical Trial Cancer Therapy Evaluation Program 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Humana Press Inc. 2003

Authors and Affiliations

  • Jack A. Roth
    • 1
  • Susan F. Grammer
    • 2
  1. 1.Department of Thoracic and Cardiovascular SurgeryUniversity of Texas M. D. Anderson Cancer CenterHouston
  2. 2.Biotechwrite: Biomedical and Science CommunicationsKalamazoo

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