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Recent Advances and Dilemmas in the Radiotherapeutic Management of Locally Advanced Non-Small Cell Lung Cancer

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Lung Cancer

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 75))

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Abstract

During the 1990s, thoracic radiotherapy (RT) combined with chemotherapy was accepted as a “new” gold standard for patients with good performance status locally advanced/inoperable non-small cell lung cancer (NSCLC). This paradigm shift away from RT alone has raised several fundamental questions: What is the optimal sequencing of chemotherapy and radiotherapy? Should standard (once-daily) RT continue to be employed? What about altered fractionation schema? Is there a role for three-dimensional conformal RT? How can the toxicity of combined modality strategies be reduced?

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Authors and Affiliations

  1. Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA

    Benjamin Movsas

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  1. Benjamin Movsas
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  1. Children#x2019;s Hospital, Los Angeles, CA

    Barbara Driscoll phd

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© 2003 Humana Press Inc., Totowa, NJ

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Movsas, B. (2003). Recent Advances and Dilemmas in the Radiotherapeutic Management of Locally Advanced Non-Small Cell Lung Cancer. In: Driscoll, B. (eds) Lung Cancer. Methods in Molecular Medicine™, vol 75. Humana Press, Totowa, NJ. https://doi.org/10.1385/1-59259-324-0:489

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  • DOI: https://doi.org/10.1385/1-59259-324-0:489

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-0-89603-920-9

  • Online ISBN: 978-1-59259-324-8

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